| 1935 | The Polish Chemical and Pharmaceutical Plant POLPHARMA was founded in Starogard Gdański. |
| 1939-1945 | In the final stage of the fight for the liberation of Pomerania, the plant was severely damaged. |
| 1949 | Reconstruction of the plant was completed. The first product manufactured after the war was redistilled water in ampoules. |
| 1951 | The Minister of Chemical Industry transformed POLPHARMA into Starogard Pharmaceutical Plant. |
| 1959 | Starogard Pharmaceutical Plant became a part of the Pharmaceutical Industry Union ‘Polfa’. |
| 01.12.1995 | The Company became a single-owner Company of the State Treasury and was renamed the POLPHARMA Joint Stock Company. |
| 06.06.2000 | Construction was completed on the largest and most modern facility in Poland for the manufacture of finished forms of drugs called ‘Solid Forms’. |
| 20.07.2000 | Privatization of POLPHARMA by the exclusive use of the Polish capital. Spectra Holding became the main shareholder. |
| 2001 | POLPHARMA Trade Office was established in Warsaw for the promotion and sale of drugs. The company opened international representative offices in Ukraine and Russia. |
| 2001 | Polpharma established the Foundation for the Development of Polish Pharmacy and Medicine, which was first foundation of this kind in Poland that was established by a private pharmaceutical company. |
| 2004 | All the manufacturing processes were adjusted to meet the EU Council Directive on Integrated Pollution Prevention and Control IPPC. Polpharma was granted an Integrated Permit. |
| 2005 | Polpharma and a team of scientists from the Technical University of Gdańsk were granted an Economic Award from the President of the Republic of Poland for the development of a new method of synthesis of alendronate sodium. |
| 2006 | Polpharma was granted GMP certificates for the production of solid forms and active pharmaceutical ingredients following the inspections conducted by the Polish Main Pharmaceutical Inspectorate. |
| 2006 | Implementation of the Integrated Management System of Environmental Health and Safety. The company was granted ISO 14001:2004 and OHSAS 18001:1999 accreditations. |